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Published: 2014-09-01

Value of the Diffusion-Weighted MRI in the Differential Diagnostics of Malignant and Benign Kidney Neoplasms – Our Clinical Experience

Yulian Mytsyk, Yuriy Borys, Iryna Komnatska, Ihor Dutka, Iryna Shatynska-Mytsyk

(Department of Radiology, Lviv National Medical University, Lviv, Ukraine)

Pol J Radiol 2014; 79:290-295

DOI: 10.12659/PJR.890604


Background: Diffusion-weighted imaging (DWI) is an MRI modality using strong bipolar gradients to create a sensitivity of the signal to the thermally-induced Brownian motions of water molecules and in vivo measurement of molecular diffusion. The apparent diffusion coefficient (ADC) is a quantitative parameter calculated from DWI images which is used as a measure of diffusion. DWI allows to obtain comprehensive information on morphological and functional state of the kidney during a single examination without contrast medium administration. The purpose of the study was to evaluate the value of DWI in differentiating benign and malignant solid kidney tumors based on the initial stage of the study.
Material and Methods: The study included 19 adult patients with pathologically verified renal tumors: 9 patients with clear cell subtype of the renal cell carcinoma, 5 patients with oncocytoma and 5 patients with angiomyolipoma (AML). In addition, 5 healthy volunteers with completely normal findings according to kidney ultrasound were included into this study and set as reference. All patients underwent renal MR imaging which included DWI with subsequent ADC measurement. MR imaging was performed with a 1.5 T body scanner using an eight-channel phased-array body coil.
Results: The mean ADC value of ccRCC was significantly lower than that of normal renal parenchyma (2.11±0.25×10−3 mm2/s vs. 3.36±0.41×10−3 mm2/s, p<0.01). There was a significant difference in ADC between the malignant and benign renal lesions: in patients with angiomyolipoma the ADC value was 2.36±0.32×10−3 mm2/s Full Text  Related Articles (0)



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Published: 2014-08-29

Doppler Ultrasound Detection of Preclinical Changes in Foot Arteries in Early Stage of Type 2 Diabetes


Jolanta Leoniuk, Adam Łukasiewicz, Małgorzata Szorc, Izabela Sackiewicz, Jacek Janica, Urszula Łebkowska

Pol J Radiol 2014; 79:283-289

DOI: 10.12659/PJR.890486

Published: 2014-08-27

Iatrogenic Hemobilia in 10-Year-Old Boy


Mateusz Łasecki, Urszula Zaleska-Dorobisz, Cyprian Olchowy, Wojciech Ugorski, Jerzy Garcarek, Dariusz Patkowski, Jacek Kurcz

Pol J Radiol 2014; 79:279-282

DOI: 10.12659/PJR.890410