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Published: 2014-10-21

Solitary Fibrous Tumour of the Pleura – Cases Analysis

Przemysław Jadczak, Wiesław Guz, Ewa Kaznowska, Radosław Ramotowski, Ewa Szalacha-Tarała, Andrzej Górecki, Antoni Samojedny

(Clinical Department of Radiology, Provincial Hospital No. 2, Rzeszów, Poland)

Pol J Radiol 2014; 79:368-373

DOI: 10.12659/PJR.890525


Background: Isolated fibrous tumor of the pleura (SFTP – Solitary fibrous tumour of the pleura/localized fibrous tumour of the pleura) is a rare primary tumour of the pleura of mesenchymal origin. In most cases, it is a benign lesion. It is composed of spindle cells similar to fibroblasts and derives probably from submesothelial mesenchyme.
The aim of the study was to analyze clinical symptoms, incidence, possibility of suggesting the diagnosis on the basis of imaging tests, and confirmation of the diagnosis in pathological tests with regard to studies of histochemistry examination.
Material and Methods: Clinical and morphological material obtained from 14 patients from Department of Thoracic Surgery of Subcarpathian Chest Disease Center treated between year 2004 and 2010 was analysed. In the first stage, selected cases of patients with isolated fibrous tumour of the pleura were chosen from the archives and the analysis of their medical history was carried out. Basic information about age, gender, medical history, smoking habit, physical examination and results of imaging, endoscopic and morphological examinations were noted. The second parallel component of the study was pathomorphological examinations of the surgical material obtained from the patients, including the assessment of morphology and immunohistochemistry.
Results: Of the 14 examined patients, fibrous tumour occurred in 8 men and 6 women. The age range of the patients was 37–73 years, with a peak attributable to the 6th decade of life. In 8 patients the tumour was detected incidentally during routine examinations. In 7 patients there were no clinical signs of res... read more

Keywords: Immunohistochemistry, Solitary Fibrous Tumor, Pleural - blood, Tomography, Spiral Computed



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